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Gene editing technologies, such as CRISPR-Cas9, enable precise modification of the genome, offering large opportunities to target age-related genes and pathways (Yu et al., 2023)

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Moreover, HGF appears to be a critical regulator of neural stem cell expansion and differentiation (Nicoleau et al., 2009) suggesting that neural as well as many types of peripheral stem cells are under the control of the HGF/c-Met system